Guide · Eyes
AREDS2 explained: the eye nutrients studied for aging eyes
If you've seen ads for eye supplements, you've probably seen the word AREDS2. It comes from one of the best-run supplement studies ever done. Here's what it found, in plain language.
What AREDS and AREDS2 are
AREDS stands for the Age-Related Eye Disease Studies, two large clinical trials run by the National Eye Institute (part of the U.S. National Institutes of Health). They tested whether high doses of certain vitamins and minerals could slow age-related macular degeneration (AMD), a leading cause of vision loss in older adults.
Who it helps
The formula helped people who already had intermediate AMD (or advanced AMD in one eye). In that group, it reduced the risk of progressing to advanced AMD by about 25%.
What it does not do
- It did not prevent AMD in people who didn't have it.
- It did not affect cataracts.
- It does not restore lost vision.
The exact AREDS2 doses
| Vitamin C | 500 mg |
|---|---|
| Vitamin E | 400 IU |
| Zinc | 80 mg |
| Copper | 2 mg |
| Lutein | 10 mg |
| Zeaxanthin | 2 mg |
The original AREDS formula used beta-carotene. AREDS2 replaced it with lutein and zeaxanthin, partly because beta-carotene raised lung-cancer risk in smokers. Current and former smokers should use AREDS2, not the original formula.
How to choose a product
- Ask your eye doctor whether you have intermediate AMD and whether AREDS2 is right for you.
- Read the Supplement Facts label and compare it with the doses above. "Inspired by AREDS2" is not the same as the AREDS2 doses.
- Check that the product has no beta-carotene if you smoke or used to smoke.
- Remember the dose is high: don't stack it with another multivitamin rich in zinc without asking your doctor.
Where to compare products
Store brands with clear labels are available at iHerb (AREDS2 search). If you're curious about a branded formula with extra herbs, see our iGenics review.